The following points highlight the top ten types of glycogen storage diseases. The types are: 1. von Gierke's Disease 2. Pompe's Disease 3. Amylopectinosis 4. MC Ardle's Disease 5. Galactosemia 6. Hereditary Fructose Intolerance 7. Lactosuria 8. Maltosuria 9. Fructosuria 10. Pentosuria. Glycogen Storage Diseases: Type # 1. von Gierke's Disease: a. The disease is due to the deficiency of [...]
In this article we will discuss about the Oxidation of Pyruvate to Acetyl-CoA. 1. Pyruvate oxidatively decarboxylated to acetyl-CoA ("active acetate") before entering the citric acid cycle. 2. The reaction is catalysed by the multi-enzyme complex consisting of several different enzymes. This complex is known as pyruvate dehydrogenase complex. 3. Pyruvate is decarboxylated in the presence of thiamine pyrophosphate (TPP) [...]
The following points highlight the top five metabolic significance of hexose monophosphate shunt. 1. CO2 is the characteristic product in this pathway which is not formed in Embden- Meyerhof pathway. This product is utilized for the synthesis of fatty acid and purine bases etc. 2. The reduced NADP (NADPH) formed in this pathway is used in the synthesis of fatty [...]