The following points highlight the nine main tests for assessing the functions of liver. The tests are: 1. Bile Pigment Metabolism in Health and in Jaundice 2. Tests for Carbohydrate Metabolism 3. Tests for Plasma Protein Concentration 4. Tests for Detoxifying Functions 5. Test for Excretion of Foreign Substances 6. Tests for Blood Coagulation 7. Tests for Serum Enzymes and [...]
The below mentioned article provides a short note on the Disorders of Plasma Membranes. Mutations affecting the protein constituents of membranes can cause many diseases. Proteins in membranes are classified as receptors, transporters, ion channels, enzymes, and structural components. All these classes are often glycosylated, so that mutations affecting this process may change their function. Almost 30 genetic disorders have [...]
The following points highlight the seven major diseases caused due to abnormalities in the synthesis of glycoproteins. 1. Many cancer cells exhibit different profiles of oligosaccharide chains on their surfaces and some of which contribute to metastasis. 2. Carbohydrate-deficient glycoprotein syndrome (CDGS) is caused due to defects in the biosynthesis of N-glycan chains (e.g., due to deficiency of Glc NAC [...]