Chargaff-Equivalence Rule for DNA | Biochemistry

In this article we will discuss about the Chargaff-equivalence rule for DNA. By 1948, a chemist Erwin Chargaff started using paper chromatography to analyse the base composition of DNA from a number of studies. In 1950, Chargaff discovered that in the DNA of different types of organisms the total amount of purines is equal to the total amount of pyrimidines [...]