In this article we will discuss about the bacterial adhesion to host cells. Before entering inside, bacteria adhere to host cells and secrete product(s) or structural products complementary to host. Hence, bacteria are found adhered to host's epithelial cells due to direct adhesion to host cells or binding to secretory products that coat host cells or bacteria. For example, teeth [...]
In this article we will discuss about the mechanisms of innate immunity in bacterial infection. Bacteria-Host Interactions at Body Surfaces: The totality of mechanisms constitutes our immunity to infection. Infection is caused rarely due to multifunctional systems of innate immunity. It is divided into those systems which (a) act at body surfaces (epithelium or submucosa), and (b) those which are [...]
In this article we will discuss about the evolution of genomes in microorganisms. The prokaryotes contain a large single, circular dsDNA molecule, usually less than 5 Mb long. In addition, they may also contain plasmids. The genome is arranged into operons. A typical prokaryotic genome contains a small amount of non-coding DNA distributed throughout the sequence. For example, E.coli contains [...]