In myocardial infarction (MI) there is necrosis of cardiac muscle due to inadequate coronary circulation. Sudden death may occur when obstruction to coronary flow is precarious. Most deaths occurring within 24 hours of the onset of attack are due to ventricular fibrillation. Anatomy of Coronary Arteries: There are three main sources of coronary arterial blood supply: (1) The anterior descending [...]
Antihypertensive drugs fall into the following four major categories according to their site of action, but there is considerable overlap: 1. Sympathetic Inhibitors 2. Vasodilators 3. Captopril 4. Diuretics. 1. Sympathetic Inhibitors: A. Central and Peripheral Inhibitors: i. Rauwolfia Group of Drugs: These are useful in mild to moderate hypertension. Rauwolfia serpentina is used in the form of dried extract, [...]
The term Cor Pulmonale was introduced by Stuart Harris (1952), Chronic Pulmonary Heart Disease (CPHD) or chronic cor pulmonale; is characterised by hypertrophy of the right ventricle, due to hypertension in the pulmonary circuit caused by chronic lung disease or pulmonary vascular pathology. But CPHD does not include cardiac damage due to pulmonary hypertension of mitral stenosis or congenital heart [...]