In this article we will discuss about the Oxidation of Pyruvate to Acetyl-CoA. 1. Pyruvate oxidatively decarboxylated to acetyl-CoA ("active acetate") before entering the citric acid cycle. 2. The reaction is catalysed by the multi-enzyme complex consisting of several different enzymes. This complex is known as pyruvate dehydrogenase complex. 3. Pyruvate is decarboxylated in the presence of thiamine pyrophosphate (TPP) [...]
In this article we will discuss about the Metabolic Reaction and Importance of Glucuronic Acid. Metabolic Reactions of Glucuronic Acid: 1. Glucose-6-phosphate is converted to glucose-1-phosphate by phosphoglucomutase. The product then reacts with UTP to form UDPG by the help of the enzyme UDPG pyrophosphorylase. 2. UDPG is oxidized to uridine di-phospho-glucuronic acid by UDPG dehydrogenase in presence of NAD+. [...]
The following points highlight the seven major endocrine influences on metabolism of carbohydrates. The endocrine influences are: 1. Insulin 2. Adrenocortical Hormones 3. Anterior Pituitary Factors 4. Epinephrine 5. Thyroid Hormone 6. Glucagon 10. Sex Hormones. 1. Insulin: a. Causes glucose transport across cell membrane by increasing the permeability of the cells. b. Increases glycogen formation in liver and muscle [...]