In this article we will discuss about the syndromes of abnormalities that occurs in humans. 1. Autosomal Trisomy: a. Down's Syndrome (DS) or Trisomy-21: Down's syndrome is named after the physician J. Langdon Down who first described this genetic defect in 1866 and it was formerly called mongolism or Mongolian idiocy. It is usually associated with a trisomic condition for [...]
The following points highlight the three major abnormalities of parathyroid function. The abnormalities are: 1. Hypoparathyroidism 2. Hyperparathyroidism 3. Deficiency of 1, 25(OH)2-D3. Parathyroid Function: Abnormality # 1. Hypoparathyroidism: a. The symptoms of hypoparathyroidism are muscular weakness, tetany and irritabilÂity. b. In case, hypothyroidism begins early in childhood, there may be stunting of growth, defective tooth development, and mental retardation. [...]
The following points highlight the five major abnormalities of thyroid function. The abnormalities are: 1. Cretinism 2. Myxoedema 3. Hashimoto's Disease 4. Toxic Goitre 5. Grave's Disease. Thyroid Function: Abnormality # 1. Cretinism: a. Growth in children is retarded. b. The child is mentally defective. He has coarse scanty hair and thick yellowish scaly skin. c. Cretinism occurs in areas [...]