In this article we will discuss about:- 1. Structure of HIV 2. Genome Organization of HIV-1 3. Steps of Entry 4. Replication 5. Assembly. Structure of HIV: HIV is different in structure from other retroviruses. HIV is of 100-120 nm diameters containing an protein envelope to which spicules of glycoprotein are attached. The envelope encloses an icosahedral capsid core that [...]
In this article we will discuss about the working of immune system in the presence of HIV. Infection is carried out through the spicules present on envelope of HIV which attach to the target cell. The gpl20 has affinity for a specific molecule, the T4 or CD4 molecule exposed on the surface of certain cells i.e. lymphocytes. The lymphocytes secrete [...]
In this article we will discuss about the structure of phage M13. M13 (or f1) phage is a filamentous phage that shows entirely alpha-helical in structure so that the molecule forms a short rod. The helical capsid is simplest measuring about 900 nm long and 9 nm in diameter. M13 is encapsulated in about 2700 copies of the major coat [...]