In this article we will discuss about the structure of picornavirus. Each capsid is composed of 60 copies of four structural proteins of which each proto-meter consists of four polypeptides known as VP1, VP2, VP3 and PV4. VP1-VP3 are exposed on the virion surface, while VP4 lies buried in close association with the RNA core (Fig. 17.21). All the VP [...]
In this article we will discus about the classification of animal viruses. Baltimore (2008) classified the animal viruses in the following seven groups according to the relationships between virion, nucleic acid and mRNA transcription Table (17.1). The RNA within the virion is known as plus (+) or sense strand because it acts as mRNA, whereas the newly synthesized RNA which [...]
In this article we will discuss about the entry of adenovirus in host cell through attachment and endocytosis steps. The virus enters into the host cell through the steps as given below: (a) Attachment: Attachment to cells is rather slow and takes several hours to reach a maximum. Viral entry occurs into the two stages. An initial interaction of the [...]