Here is a list of nine aminoglycoside antibiotics. 1. Streptomycin: 1. Isolated from streptomyces griseus in 1943. 2. Very soluble in water. 3. Stable compared with penicillin. 4. Pure dry powder remain full potency at room temperature for at least 2 years. 5. Intestinal absorption poor. 6. Used in the treatment of enteritis. 7. Slow absorption from I/M route. 8. [...]
After reading this article we will discuss about:- 1. Chemistry of Tetracyclines 2. Classification of Tetracyclines 3. Antibacterial Spectrum 4. Bacterial Resistance 5. Mechanism of Action 6. Administration 7. Pharmacokinetics 8. Side Effects 9. Precautions 10. Therapeutic Indications 11. Dosage Regimens. Chemistry of Tetracyclines: As the name suggests, chemically tetracyclines have four partially unsaturated cyclohexane rings and are the close [...]
Here is a list of various macrolide antibiotics. 1. Erythromycin: (i) This macrolide antibiotic was isolated from Streptomyces erythreus, a soil- born organism in 1952. (ii) It consists of two sugars, desosamine and cladinose, which are attached to erythronolide, a macro cyclic lactone. (iii) It is slightly water soluble. (iv) The antibiotic remains more active, in alkaline medium than at [...]