Read this article to learn about the nine things of protein engineering. 1. Increasing the Stability and Biological Activity of Proteins: By increasing the half-lives or thermo stability of enzymes/proteins, their industrial applications or therapeutic uses can be more appropriately met. Some of the approaches for producing proteins with enhanced stability are described below. 2. Addition of Disulfide Bonds: Significant [...]
This article throws light upon the five stages of protein biosynthesis. The five stages are: (1) Requirement of the Components (2) Activation of Amino Acids (3) Protein Synthesis Proper (4) Chaperones and Protein Folding and (5) Post-Translational Modifications of Proteins. The protein synthesis which involves the translation of nucleotide base sequence of mRNA into the language of amino acid sequence [...]
John J. Berzelius (1838) first coined the term 'protein' (Gr. proteios — of the first rank) to stress the importance of this class of polymers. Proteins are the macromolecules composed of one or more polypeptide chains, each of which is a mixed polymer of L-a-amino acid residues joined end-to-end by peptide bonds. Monomeric protein consists of single polypeptide chain, e.g., [...]