Nucleotides Metabolism and De Novo Synthesis of Nucleotides
Let us make an in-depth study of the nucleotides metabolism with special emphasis on de novo synthesis of nucleotides. Nucleotide consists of a purine or pyrimidine base plus a pentose sugar (ribose or deoxyribose) and a phosphoryl group (H3PO4). The purine ring consists of a 5-membered imidazol ring fused to a six-membered ring structure with two common or bridge carbon [...]