Archive | Molecular Biology

DNA and Importance of Proteins | Molecular Biology

The length of DNA double helix is calculated in a typical mammalian cell (simply by multiplying the total number of bp with distance between two consecutive bp, that is, 6.6 x 109 bp x 0.34 x 10-9m/bp), which approximately comes out to be 2.2 meters. A length that is far greater than the dimension of a typical nucleus (approximately 10-6 [...]

By |2015-08-27T17:08:50+00:00March 4, 2014|Molecular Biology|Comments Off on DNA and Importance of Proteins | Molecular Biology

Protein Synthesis: Control of Protein Synthesis |Biology

Control of Protein Synthesis! (i) A Mechanism for the control of protein synthesis by Adenovirus VA RNAI: In the absence of VA RNAI protein synthesis process fails in adenovirus infected HeLa cells. This is due to defective initiation. The defect results from phosphorylation of the initiation factor elF-2 on its alpha subunit. The protein kinase is responsible as the DSRNA-activated [...]

By |2015-08-27T17:09:07+00:00March 4, 2014|Molecular Biology|Comments Off on Protein Synthesis: Control of Protein Synthesis |Biology
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