Archive | Medical Microbiology

Metronidazole: Structure and Adverse Effects| Antibiotics

In this article we will discuss about:- 1. Structure of Metronidazole 2. Mechanism of Action of Metronidazole 3. Adverse Effects. Structure of Metronidazole: Metronidazole is a nitroimidazole, the class of therapeutic drugs used mainly in the treatment of infections caused by susceptible organisms, particularly anaerobic bacteria and protozoa. Metronidazole (1-(β-hydroxyethyl)-2-methyI-5-nitroimidazole), the chemical structure of which is given in Fig. 45.17 [...]

By |2016-09-16T06:07:05+00:00September 16, 2016|Medical Microbiology|Comments Off on Metronidazole: Structure and Adverse Effects| Antibiotics
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Chloramphenicol: Structure and Mechanism of Action | Antibiotics

In this article we will discuss about:- 1. Structure of Chloramphenicol 2. Antibiotic Spectrum of Chloramphenicol 3. Mechanism of Action. Structure of Chloramphenicol: Chemically, chloramphenicol is a simple structure (Fig. 45.12) made up of nitrobenzene ring bonded with non-ionic chlorine. It consists of two unusual components—one nitro (-NO2) group and a dichloroacetyl (-COCHCl2) group. The molecule possesses two asymmetric carbon [...]

By |2016-09-16T06:19:05+00:00September 16, 2016|Medical Microbiology|Comments Off on Chloramphenicol: Structure and Mechanism of Action | Antibiotics
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Streptomycin: Discovery, Structure and Mechanism | Antibiotics

In this article we will discuss about:- 1. Structure of Streptomycin 2. Antibiotic Spectrum of Streptomycin 3. Mechanism of Action 4. Dependence. Structure of Streptomycin: Streptomycin is characterised chemically as an aminoglycoside antibiotic. It consists of three components linked glycosidically (by ether bonds): (i) Streptidine (inositol with two guanido groups), (ii) Streptose (methyl pentose), and (iii) Streptoscamine (N-methyl-L-glycosamine) as shown [...]

By |2016-09-16T06:19:15+00:00September 16, 2016|Medical Microbiology|Comments Off on Streptomycin: Discovery, Structure and Mechanism | Antibiotics
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