The below mentioned article provides notes on cell-mediated (cellular) immunity. The cell-mediated or cellular immunity is that where the T-lymphocytes destroy other cells having antigens on their surface without any mediation by antibodies. The precursors of T-lymphocytes produced by stem cells of bone marrow pass through liver and spleen before reaching the thymus where they are processed, hence called thymus-dependent [...]
The B and T-lymphocytes that are yet to encounter an antigen are called naive B and naive T-cells. The naive B-cells that encounter the antigen, proliferate and differentiate into two types of cells: the antibody-secreting plasma cells and the memory B-cells. The plasma cells form the basis of primary immune response, which is the response mounted by the immune system [...]
Most antigens offer multiple epitopes (antigenic determinants) and therefore induce proliferation and differentiation of a variety of B-cell clones, each derived from a B-cell that recognizes a particular epitope. Polyclonal antibodies represent a mixture of antibodies synthesized by variety of such B-lymphocyte (B-cell) clones. The resulting polyclonal antibodies in the antiserum are heterogenous, comprising a mixture of antibodies, each specific [...]