In this essay we will discuss about the drugs used for the treatment of malaria. 1. Quinine: It is an alkaloid obtained from the bark of the Cinchona tree and remains the best drug for all complicated malaria, especially chloroquine resistant P. falciparum infection. Pharmacokinetics: Quinine is well absorbed orally, about 70% is bound to plasma proteins and CSF penetration [...]
In this essay we will discuss about the drugs used for the treatment of dyspepsia and gastro-esophageal reflux disease:- 1. Non-Systemic Antacids 2. Systemic Antacid 3. Alginates 4. Surface Anesthetics 5. Acid Release Inhibitors 6. Pro-Kinetic Drugs or Motility Stimulants. 1. Non-Systemic Antacids: Aluminum and magnesium containing antacids are relatively insoluble, very poorly absorbed, longer acting and most suitable for [...]
In this essay we will discuss about the drugs used for the treatment of chronic inflammatory disease:- 1. Corticosteroids 2. 5-Amino Salicylates (ASA) Compounds 3. Immunosuppressants 4. Antibacterial Drugs. 1. Corticosteroids: Corticosteroids are used to produce remission in both disorders. Prednisolone is given orally until the disease remits, then it is reduced stepwise. Alternatively budesonide, a retarded-release steroid, may be [...]