In this article we will discuss about the structure and synthesis of telomere. Structure of Telomere: Molecular genetic studies have shown that the telomere consists of several short sequences which are tandemly repeated (Table 8.8). The general formula for the composition of the repeating units in one strand of the telomeres of all the eukaryotes is as follows: 5' Cn [...]
In this article we will discuss about the inversions in humans which occurs when the genes in a section of a chromosome is reversed. Pericentric Inversion: There are a number of reports of pericentric inversions in human. Breaks occur in both, short (p) and long (q) arms of the chromosomes. The length of inverted segment can be precisely identified by [...]
In this article we will discuss about the genetical and cytological methods of locating inversion break points. Cytological Location: Cytological analysis is an important method of the physical location of the break points of inversion. (a) In plants like maize, and other organisms where pachytene analysis is easy, the breakpoints can be located by measuring the position of the inversion [...]