In this article we will discuss about:- 1. Introduction to Apoptosis 2. Cellular Events of Apoptosis 3. Mechanism 4. Importance. Introduction to Apoptosis: Every normal living cell of animals, plants and even bacteria are mortal. I.e., they must die after some time. Cell death is a finely tuned programme inherent in the cells genetic machinery. This normal cell death which [...]
A proteinaceous factor termed as maturation promoting factor (MPF), subsequently renamed as mitosis promoting factor, is identified and purified (Masui, Markert, Mailer). MPF is a heterodimer complex between kinase - a catalytic sub- unit and cyclin - a regulatory subunit (Fig. 5.27A). Kinase enzyme brings about phosphorylation of specific target proteins at different stages of the cell cycle which is [...]
In this article we will discuss about:- 1. Introduction to Dynamics of Chromosome 2. Events of Chromosome Movement 3. Mechanism. Introduction to Chromosome Movement: Chromosomes are involved in a series of directed movements during both mitosis and meiosis. With the separation of the sister chromatids/homologues at anaphase, the equilibrium is broken, the chromosomes move towards the poles at the rate [...]