The below mentioned article provides a short note on the Acidic Amino Acids. The acidic amino acids are: 1. Aspartic Acid (α-amino-succinic acid). 2. Glutamic Acid (α-amino glutaric acid). Structure: Biological Importance of Acidic Amino Acids : 1. These amino acids are nonessential and readily synthesized in the body. 2. These are metabolically the most reactive of the amino acids. [...]
Amino acids forming pyruvate are convertible to acetyl-CoA. In addition to this, 5 amino acids form acetyl-CoA directly, without first forming pyruvate. Phenylalanine: Phenylalanine (an essential amino acid) is converted to tyrosine by phenylalanine hydroxylase; tetrahydropteridine, NADPH and O, are required. The reaction is not reversible. The catabolism of phenylalanine and tyrosine may be discussed under the following heads: 1. [...]
The following points highlight the fourteen major diseases caused due to errors in protein metabolism. The diseases are: 1. Albinism 2. Tyrosinosis 3. Tyrosinernia 4. Phenylketonuria 5. Alkaptonuria 6. Maple Syrup Urine Disease 7. Hartnup's Disease 8. Glycinuria 9. Primary Hyperoxaluria 10. Cystinuria 11. Cystinosis 12. Homocystinuria 13. Histidinemia 14. Hypervalinemia. Errors in Protein Metabolism: Disease # 1. Albinism: a. [...]