In this article we will discuss about the History and Advancement of Clinical Biochemistry. Clinical Biochemistry: From the time of Hippocrates (C.460-C.375 B.C.) the crude examination of body fluids including urine had been done. Thomas Willis, in the second half of the 17th century wrote a dissertation on urine and did the sweet taste to differentiate between the two types [...]
In this article we will discuss about the Intercellular Contact and Communication of Plasma Membranes. Cells have developed specialized regions on their membranes for intercellular communication. Gap junctions mediate and regulate the passage of ions and small molecules through a narrow hydrophilic pore connecting the cytoplasm's of adjacent cells. These pores are composed of subunits called "connexions". Connexions consist of [...]
In this article we will discuss about the Genetic Diseases:- 1. Major Classes of Genetic Diseases 2. Pathologic Consequences 3. Early Diagnosis of Certain Inborn Errors to Avoid Permanent Damage 4. Successful Treatment. Major Classes of Genetic Diseases: Genetic diseases can be divided into three classes: i. Chromosomal Disorders. ii. Monogenic (Classic Mendelian) Disorders. iii. Multifactorial Disorders. i. Chromosomal Disorder: [...]