In this article we will discuss about the oxidative decarboxylation of pyruvic acid. We know that anaerobiosis the pyruvic acid formed during glycolysis reacts with NADH which accumulates to give lactic acid (or ethanol) and thus permits the regeneration of NAD+. But when oxygen is available, NADH is reoxidized thanks to the electrons carrier system, and the pyruvic acid is [...]
In this article we will discuss about the inhibition of glycolysis by oxygen. Some controls, particularly hormonal, are carried out on glycolysis. We will examine here only the effect of oxygen known as the Pasteur effect because Pasteur was the first scientist to observe that in yeast, glucose was less rapidly consumed in aerobiosis than in anaerobiosis. In other words, [...]
Monosaccharides, and particularly glucose, owe their importance to the fact that their oxidation provides the living organisms with a major part of the energy they require. Furthermore, the carbon atoms of glucose can be found in a large number of compounds (amino acids, fatty acids, sterols, glycerol, etc.). In the study of the metabolism of carbohydrates we will therefore come [...]