Read this article to learn about the gene libraries, genomic libraries and cDNA libraries. DNA (Gene) Libraries: A DNA library is a set of cloned fragments that collectively represent the genes of a particular organism. Particular genes can be isolated from DNA libraries, much as books can be obtained from conventional libraries. The secret is knowing where and how to [...]
Read this article to learn about the concept, labelling and translation of gene probes. Concept of Gene Probes: The information needed to produce a gene probe may come from many sources but with the development and sophistication of genetic database, gaining this knowledge is usually one of the first stages. In some cases it is possible to use related proteins [...]
Read this article to learn about the concept and structure of operon mode in gene regulation. Jacob and Monod (1961) gave the concept of Operon model to explain the gene regulation in prokaryotes using simple experiments to grow E. coli in petriplates containing histidine, lactose or lactose and glucose in the medium (Fig. 9.2). When histidine is present in the [...]